Safety margins

≥ 18 years

Weight	ROA	Dosage
	ROA: po	Dosage: min. 125mg 2 dd to max. 500mg 2 dd
	ROA: iv	Dosage: min. 750mg 3 dd to max. 3000mg 3 dd
	ROA: iv	Dosage: min. 2250mg to max. 4500mg continuous per 24 hours
Comments: Standaard dosis intraveneus: 3 dd 1500 mg. Standaard dosis oraal: 2 dd 250-500 mg. Bij continue infusie 1500 mg oplaaddosis. Hogere doses indien geïndiceerd tot 9000 mg/24 uur.

Dosage for "I" sensitivity

≥ 18 years

Weight	ROA	Load	Dosage
	ROA: iv	Load: -	Dosage: 1500mg 3 dd
Comments: NB: hoge dosering is zelfde als standaard dosering voor gram-negatieve bacteriën

Kidney function

≥ 18 years

ROA	GFR	Dosage	Interval	Comments
ROA: iv
	GFR: 10 - 30	Dosage: standaarddosering	Interval: 12 Hours
	GFR: <10	Dosage: standaarddosering	Interval: 24 Hours

Renal elimination: 95%

Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: 750 mg 2 dd iv.

Hemo dialysis: 750 mg 2 dd iv, op dialysedagen tweede dosis na dialyse.

CAV / VVHD: Continue venoveneuze hemodialyse/hemo(dia)filtratie: 3 g continu of 1500 mg 3x per dag

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

• http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
• http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16

For individual advice, consult an expert on site.

Metadata

Swab vid: M-502206.1
Updated: 03/06/2024 - 09:55
Status: Published

External links

• Farmacotherapeutisch Kompas - Cefuroxim

Menu position

• antibacterial