meropenem
J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DH - Carbapenems -> J01DH02 - Meropenem
Administration category:
Free
Medicine group:
antibacterial
Brand name:
Meronem
Safety margins
| Weight | ROA | Dosage | |
|---|---|---|---|
|
ROA: iv |
Dosage: min. 3000mg to max. 6000mg continuous per 24 hours |
||
|
ROA: iv |
Dosage: min. 1000mg 3 dd to max. 2000mg 3 dd |
||
|
Comments:
Standaarddosis 3000 mg/dag, bij uitzondering tot 6000 mg/dag. Bij continue infusie van 3 g/24h: 1000 mg oplaaddosis vooraf. Op IC voorkeur voor continue toediening. |
|||
Dosage for "I" sensitivity
| Weight | ROA | Load | Dosage |
|---|---|---|---|
|
ROA: iv |
Load: 2000mg |
Dosage: 6000mg continuous per 24 hours |
Kidney function
| ROA | GFR | Dosage | Interval | Comments |
|---|---|---|---|---|
| ROA: iv | ||||
|
GFR: 30 - 50 |
Comments: 2000-4000 mg/24h |
|||
|
GFR: 10 - 30 |
Comments: Eerste dosis 1000-2000 mg, daarna 1000-2000 mg/24h |
|||
|
GFR: <10 |
Comments: Eerste dosis 1000-2000 mg, daarna 500-1000mg/24h |
|||
Renal elimination:
60-70%
Dosage:
dependent on kidney function
Renal function-replacement therapy
CAPD: Eerste dosis 1000-2000 mg, gevolgd door 1000-2000 mg/24h
Hemo dialysis: Eerste dosis 1000-2000 mg, daarna 500-1000 mg/24h + op dialysedag 500-1000 mg na de dialyse.
CAV / VVHD: 2000-3000 mg/24h
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-502907.1
Updated: 10/14/2025 - 11:03
Status: Published