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Home Medication antibacterial

ciprofloxacine

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01M - Quinolone Antibacterials -> J01MA - Fluoroquinolones -> J01MA02 - Ciprofloxacin
Administration category: Free Medicine group: antibacterial Brand name: Ciproxin

Safety margins

≥ 18 years
Weight ROA Dosage
ROA:
 po 		Dosage:
 500mg 2 dd to max. 750mg 2 dd
ROA:
 iv 		Dosage:
 400mg 2 dd to max. 400mg 3 dd
Comments:

Bij botinfecties, infecties met Pseudomonas species of infecties met intermediaire gevoelige micro-organismen hoog doseren (2 dd 750 mg p.o. of 3 dd 400 mg i.v.).

Dosage for "I" sensitivity

≥ 18 years
Weight ROA Load Dosage
ROA:
 po 		Load:
 - 		Dosage:
 750mg 2 dd
ROA:
 iv 		Load:
 - 		Dosage:
 400mg 3 dd

Kidney function

≥ 18 years
ROA GFR Dosage Interval Comments
ROA: po
GFR:
 10 - 30 		Interval:
 24 Hours 		Comments:
 1 dd 500 - 750 mg p.o.. Bij ernstig ziek 2 dd 500 -750 mg.
GFR:
 <10 		Interval:
 24 Hours 		Comments:
 1 dd 500 mg p.o.
ROA: iv
GFR:
 10 - 30 		Interval:
 24 Hours 		Comments:
 1 dd 400 mg i.v.. Bij ernstig ziek 2 dd 400 mg i.v.
GFR:
 <10 		Interval:
 24 Hours 		Comments:
 1 dd 400 mg i.v.

Notes GFR general:

Bij eGFR 10-30: Bij botinfecties, infecties met Pseudomonas species of infecties met intermediaire gevoelige micro-organismen hoog doseren (2 dd 750 mg p.o. of 2 dd 400 mg i.v.).
Renal elimination: 40-70%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: 1dd 400 mg i.v. of 1 dd 500 mg per os. Indien ernstig ziek 2dd 400 mg i.v. of 2 dd 500 mg p.o.

Hemo dialysis: 1dd 400 mg i.v. of 1 dd 500 mg per os. Indien ernstig ziek 2dd 400 mg i.v. of 2 dd 500 mg p.o.

CAV / VVHD: Normale dosering toepassen.

Interactions

Interaction with (ATC): Interaction with: Expected effect:
Interaction with (ATC):
 R03DA04 - Theophylline 		Interaction with:
 		Expected effect:
 verhoging plasmaconcentratie theofylline
Interaction with (ATC):
 		Interaction with:
 ijzerzouten 		Expected effect:
 vermindering absorptie ciprofloxacine
Interaction with (ATC):
 		Interaction with:
 aluminium- of magnesium bevattende antacida 		Expected effect:
 vermindering absorptie ciprofloxacine
Interaction with (ATC):
 A02BX02 - Sucralfate 		Interaction with:
 		Expected effect:
 vermindering absorptie ciprofloxacine

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.

General comments

Bij nierfunctiestoornissen of nierfunctievervangende therapie eventueel doseren op geleide van de ciprofloxacineconcentratie. 

Metadata

Swab vid: M-501829.1
Updated: 09/08/2023 - 12:12
Status: Published

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